Approximately seven percent of breast cancer cases are caused by mutations in the BRCA1 or BRCA2 genes.¹   People who carry a mutation in either of these genes have a condition called Hereditary Breast and Ovarian Cancer (HBOC) syndrome.^2-3 They have an up to 87 percent risk of developing breast cancer by age 70. In addition, mutation carriers who have already been diagnosed with cancer have a significantly increased risk of developing second cancer in the future. Myriad offers genetic testing that can be used to identify people who carry a BRCA1 orBRCA2 gene mutation.

Risk Factors for Hereditary Breast Cancer

Risk Factors for Hereditary Breast Cancer

Knowing your potential Risk Factors for Hereditary Breast Cancer (HBOC) can help you and your healthcare professional make better, more informed decisions about your health, before the onset of cancer or before a second cancer has had a chance to develop. Genetic testing for hereditary breast and ovarian cancer with the Myriad myRisk^®Hereditary Cancer panel should be considered if:^*

You:

• Have had breast cancer at age 50 or younger
• Have had triple negative breast cancer
• Have ever had ovarian cancer
• Are male and have had breast cancer at any age
• Have had a male relative diagnosed with breast cancer
• Are of Ashkenazi Jewish descent and have a personal or family history of breast, ovarian or pancreatic cancer

Your Family:

• Has had someone diagnosed with breast cancer before age 50
• Has had someone diagnosed with ovarian cancer
• Has had two breast cancers in the same person or on the same side of the family
• Has had a male family member diagnosed with breast cancer
• Has had someone diagnosed with triple negative breast cancer at any age
• Has three or more family members with HBOC-associated^** cancer on the same side of the family
• Has had a previously identified BRCA1 or BRCA2 mutation in the family