Coronaviruses were first discovered in the 1960s. Is there cross-reactivity between SARS-CoV-2 antibodies with any of these other coronaviruses?

2020-05-15T19:39:00+00:00

Sonora Quest is performing a test kit manufactured by EUROIMMUN, a PerkinElmer company. The assay kit package insert6 states that in the validation of the ELISAs, no cross-reactions to antibodies against worldwide-distributed coronaviruses were detected. Cross-reactions with antibodies against the closely related SARS-CoV(-1) and other known human coronaviruses (HKU1, NL63, OC43, or 229E) cannot be [...]

Coronaviruses were first discovered in the 1960s. Is there cross-reactivity between SARS-CoV-2 antibodies with any of these other coronaviruses?2020-05-15T19:39:00+00:00

What is the specificity of the EUROIMMUN Anti-SARS-CoV-2 ELISA IgG antibody test?

2020-05-15T19:37:52+00:00

As stated in literature provided by EUROIMMUN, analytical specificity of the EUROIMMUN Anti-SARS-CoV-2 ELISA IgG antibody test is 98.5-99%. Due to the low homology of the SARS-CoV-2 S1 protein to the human coronavirus family (HCoV-229E, HCoV-NL63, HCoV-HKU1 or HCoV-OC43), cross-reactions to most of the human pathogenic representatives of this virus family are virtually excluded.

What is the specificity of the EUROIMMUN Anti-SARS-CoV-2 ELISA IgG antibody test?2020-05-15T19:37:52+00:00

What is the importance of sensitivity vs specificity in antibody testing for COVID-19?

2020-05-15T19:36:15+00:00

Sensitivity is normally used in the context of measuring sensitivity to detect the disease, however, in the context of serology, you are only measuring sensitivity to antibodies, not SARS-CoV-2. Because antibody testing is not used for diagnosis, sensitivity is less important than specificity. The focus is on maximizing specificity for IgG so that we have [...]

What is the importance of sensitivity vs specificity in antibody testing for COVID-19?2020-05-15T19:36:15+00:00

Will the antibody testing need to be on its own requisition, or can it be combined with other tests?

2020-05-15T19:32:17+00:00

The antibody testing does not need to be on its own requisition. However, if you’re submitting both a molecular test and an antibody test, the molecular test must be submitted on its own requisition in its own specimen bag.

Will the antibody testing need to be on its own requisition, or can it be combined with other tests?2020-05-15T19:32:17+00:00

I don’t have insurance, what can I do?

2020-05-15T19:30:34+00:00

To apply for AHCCCS or to obtain additional information, patients can visit https://azahcccs.gov/Members/GetCovered/apply.html or call the Applicant & Member Services 1(855)HEA-PLUS (1-855-432-7587). Calls are answered Monday through Friday 8 a.m. – 5 p.m.

I don’t have insurance, what can I do?2020-05-15T19:30:34+00:00